On Sunday, February 9, 2025, an Orange County Jail inmate housed in the Correctional Medical Services wing of a local hospital died while inside custody. The decedent, a 72-year-old Asian male was in-custody for CPC 664/187 – Attempted murder, CPC 451(a) – Arson causing great bodily injury, CPC 451(b) – Arson to inhabited structure/dwelling, and CPC 451(a)(1) – Aggravated arson with a prior. The decedent's manner and means of death are awaiting final determination by the Orange County Coroner.

On Friday, January 26, 2024, an Orange County Jail inmate housed at the Central Men’s Jail in Module C died while inside custody. The decedent is a 57-year-old Hispanic male who was awaiting trial.  The decedent's manner and means of death are awaiting final determination by the Orange County Coroner.”

On Monday, February 5, 2024, an Orange County Jail inmate housed at the Central Men’s Jail in Module D died at the Orange County Global Medical Center, Santa Ana. The decedent was a 41-year-old white male who was awaiting arraignment.  The decedent's manner and mode of death are awaiting final determination by the Orange County Coroner.

On Friday, January 5, 2024, an Orange County Jail inmate housed at the Intake Release Center in Module K died at Orange County Global Medical Center, Santa Ana. The decedent is a 28-year-old Hispanic female who was sentenced and awaiting to be released from custody at the end of the month.  The decedent's manner and means of death are awaiting final determination by the Orange County Coroner.

On Thursday, January 11, 2024, an inmate was remanded into Orange County Sheriff’s custody via bedside arraignment at the Orange County Global Medical Center.  On Sunday, January 14, 2024, the inmate died while still receiving medical care and prior to being housed in the Orange County Jail.  The decedent is a 34-year-old white male who was awaiting trial.  The decedent's manner and means of death are awaiting final determination by the Orange County Coroner.

On Friday, March 8, 2024, an Orange County Jail inmate housed at the Theo Lacy Facility in Module Q died while inside custody. The decedent is a 46-year-old white male who was awaiting to be transferred to Riverside County Sheriff’s custody.  The decedent's manner and means of death are awaiting final determination by the Orange County Coroner.

On Monday, March 11, 2024, an Orange County Jail inmate housed at the Central Men’s Jail in Module B died at the Orange County Global Medical Center, Santa Ana. The decedent was a 36-year-old Hispanic male who was awaiting trial.  The decedent's manner and mode of death are awaiting final determination by the Orange County Coroner.

On Monday, June 24, 2024, an Orange County Jail inmate housed at the Theo Lacy Facility in Module O died at UCI Medical Center, Orange. The decedent is a 51-year-old Hispanic male who was awaiting trial. The decedent's manner and means of death are awaiting final determination by the Orange County Coroner.

On Friday, Feb. 21, 2025, an inmate who was housed at the Intake Release Center in Santa Ana died at OC Global Medical Center in Santa Ana. The inmate, Juan Vasquez Pulido, 38, no known residence, was booked into jail on Feb. 5, 2025, by the Anaheim Police Department for drug related offenses. The same day, Pulido was the victim of an assault by another inmate while on the booking loop of the Intake Release Center. On Feb. 21, Pulido died while at the hospital. The decedent's manner and means of death are awaiting final determination by the Orange County Coroner.

On Monday, Mar. 31, 2025, an inmate who was housed at the Intake Release Center in Santa Ana died while in custody. The decedent, a 55-year-old male, was in custody without bail for PC 192(c)(1) – Vehicle Manslaughter with Gross Negligence, PC 245(a)(1) – Assault with a Deadly Weapon, VC 20001(a) – Hit and Run with Injury. The decedent's manner and means of death are awaiting final determination by the Orange County Coroner.